Peer Reviewed

Scientific Journals

Papers in

peer-reviewed journals


book chapters

Aging Expert Urges Government Leaders to Accelerate Research in Aging

Leading expert on aging sees extending healthy lifespan as the most plausible solution and a source of growth for economies of the developed countries Read more


Ageless Generation: Interview with Alex Zhavoronkov

The title of Alex Zhavoronkov’s new book “The Ageless Generation: How Advances in Biomedicine Will Transform the Global Economy” well conveys its important theme. Read more


Living to 150: How Will Society Adapt?

Many people express concern about tampering with what they consider the natural order of things. Is it ethical or even reasonable to manipulate the human lifespan? Read more


A New Kind Of Second Opinion — A Price

Our very own Michael Rose has recently been invited to speak on a live interview where discusses the aging process in regards to modern science and medicine. Read more


Yahoo Finance about OncoFinder Project Read



Skolkovo: IBM, Skolkovo Foundation and FORAC will jointly develop targeted medicine platform Read



East-West Digital News: Skolkovo and IBM team up to “extend the healthy productive lives of patients with cancer and other age-related diseases” Read


Lecture — Biomedical discoveries and the ageless generation Read



Forbes: Why We Should Look Forward To Living To 120 And Beyond? Read


Huffington Post: 13 Reasons Why We Will Live Longer Than Our Parents Read


Science Daily: Featured Research — Algorithm developed for anti-aging remedy search Read


Comment by Bani Sodermark Read


The International Aging Research Portfolio Launches Read

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  • A method for predicting target drug efficiency in cancer based on the analysis of signaling pathway activation. Artem Artemov, Alexander Aliper, Michael Korzinkin, Ksenia Lezhnina, Leslie Jellen, Nicolay Zhukov, Sergey Roumiantsev, Nurshat Gaifullin, Alex Zhavoronkov, Nicolas Borisov,Anton Buzdin. Oncotarget. 2015
  • Combinatorial high-throughput experimental and bioinformatic approach identifies molecular pathways linked with the sensitivity to anticancer target drugs. Larisa Venkova, Alexander Aliper, Maria Suntsova, Roman Kholodenko, Denis Shepelin, Nicolas Borisov, Galina Malakhova, Raif Vasilov, Sergey Roumiantsev, Alex Zhavoronkov, Anton Buzdin. Oncotarget. 2015
  • Molecular functions of human endogenous retroviruses in health and disease. Suntsova M, Garazha A, Ivanova A, Kaminsky D, Zhavoronkov A, Buzdin A. Cell Mol Life Sci. 2015 Jun 18. [Epub ahead of print]
  • Pathway Activation Strength (PAS) is a Novel Independent Prognostic Biomarker for Cetuximab Sensitivity in Colorectal Cancer Patients. Qingsong Zhu, Evgeny Izumchenko, Alexander Aliper, Evgeny Makarev, Keren Paz, Anton Buzdin, Alex Zhavoronkov, and David Sidransky. Human Genome Variation. (Nature Publishing Group) 2015.
  • New bioinformatic tool for quick identification of functionally relevant endogenous retroviral inserts in human genome. A.Garazha, A.Ivanova, M.Suntsova, G.Malakhova, S.Roumiantsev, A.Zhavoronkov, A. Buzdin. Cell Cycle. 2015 Apr 8:0. IF: 5.0
  • Screening and personalizing nootropic drugs and cognitive modulator regimens in silico. Jellen LC, Aliper A, Buzdin A, Zhavoronkov A. Front Syst Neurosci. 2015 Feb 6;9:4. doi: 10.3389/fnsys.2015.00004. eCollection 2015.
  • Signaling pathway activation drift during aging: Hutchinson-Gilford Progeria Syndrome fibroblasts are comparable to normal middle-age and old-age cells. Alexander Aliper, Antonei Benjamin Csoka, Anton Buzdin, Tomasz Jetka, Sergey Roumiantsev, Alexey Moskalev, Alex Zhavoronkov.Aging (Albany NY). 2015, IF: 5.1
  • Pathway activation profiling reveals new insights into Age-related Macular Degeneration and provides avenues for therapeutic interventions. Makarev E, Cantor C, Zhavoronkov A, Buzdin A, Aliper A, Csoka AB. Aging (Albany NY). 2014 Dec 27. [Epub ahead of print] IF: 5.1
  •  Interactome analysis of myeloid-derived suppressor cells in murine models of colon and breast cancer. Aliper AM, Frieden-Korovkina VP, Buzdin A, Roumiantsev SA, Zhavoronkov A. Oncotarget 2014, Sep 16. [Epub ahead of print] IF: 6.6
  • Novel robust biomarkers for human bladder cancer based on activation of intracellular signaling pathways. K. Lezhnina, O. Kovalchuk, A.A. Zhavoronkov, M.B. Korzinkin, A.A. Zabolotneva, P.V. Shegay, D.G. Sokov, N.M. Gaifullin, I.G. Rusakov, A.M. Aliper, S.A. Roumiantsev, B.Y. Alekseev, N.M. Borisov, and A.A. Buzdin. Oncotarget, 2014, Oct 15;5(19):9022-32. IF: 6.6
  • Signaling pathway activation profiles make better markers of cancer than expression of individual genes. N.M. Borisov, N.V. Terekhanova, A.M. Aliper, L.S. Venkova, P.Yu. Smirnov, S.Roumiantsev, M.B. Korzinkin, A.A. Zhavoronkov, A.A. Buzdin. Oncotarget, 2014 Oct 30;5(20):10198-205 IF: 6.6
  • The OncoFinder algorithm for minimizing the errors introduced by the high-throughput methods of transcriptome analysis. Anton A. Buzdin, Alex A. Zhavoronkov,  Mikhail B. Korzinkin,  Sergey A. Roumiantsev,  Alexander M. Aliper,  Larisa S. Venkova,  Philip Y. Smirnov and Nikolay M. Borisov. Front. Mol. Biosci., 26 August 2014 | doi: 10.3389 Stimulation of Cell Proliferation by Carnosine: Cell and Transcriptome Approaches. K. S. Vishnyakova, M. A. Babizhayev, A. M. Aliper, A. A. Buzdin, A. V. Kudryavzeva, and Y. E. Yegorov. Molecular Biology, 2014, Vol.48, No5, 718-726 IF: 0.7
  • Silencing AML1-ETO gene expression leads to simultaneous activation of both pro-apoptotic and proliferation signaling. Spirin PV, Lebedev TD, Orlova NN, Gornostaeva AS, Prokofjeva MM, Nikitenko NA, Dmitriev SE,Buzdin AA, Borisov NM, Aliper AM, Garazha AV, Rubtsov PM, Stocking C, Prassolov VS. Leukemia (Nature Publishing Group). 2014 Apr 14. doi: 10.1038/leu.2014.130. IF: 9.4
  • Oncofinder, a new method for the analysis of intracellular signaling pathway activation using transcriptomic data. Buzdin AA, Zhavoronkov AA, Korzinkin MB, Venkova LS, Zenin AA, Smirnov PY, Borisov NM. Front Genet. 2014 Mar 25;5:55. doi: 10.3389/fgene.2014.00055.
  • A role for G-CSF and GM-CSF in nonmyeloid cancers Aliper AM, Frieden-Korovkina VP, Buzdin A, Roumiantsev SA, Zhavoronkov A. Cancer Med. 2014 Aug;3(4):737-46. doi: 10.1002/cam4.239. Epub 2014 Apr 2.
  • Signaling pathway cloud regulation for in silico screening and ranking of the potential geroprotective drugs. Zhavoronkov A, Buzdin AA, Garazha AV, Borisov NM, Moskalev AA. Front Genet. 2014 Mar 3;5:49. doi: 10.3389/fgene.2014.00049.
  • Genetics and epigenetics of aging and longevity. Moskalev AA, Aliper AM, Smit-McBride Z, Buzdin A, Zhavoronkov A. Cell Cycle. 2014 Apr 1;13(7):1063-77. doi: 10.4161/cc.28433. Epub 2014 Mar 6. IF: 4.99
  • A systematic experimental evaluation of microRNA markers of human bladder cancer. Zabolotneva AA, Zhavoronkov AA, Shegay PV, Gaifullin NM, Alekseev BY, Roumiantsev SA, Garazha AV, Kovalchuk O, Aravin A, Buzdin AA. Front Genet. 2013 Nov 15;4:247. doi: 10.3389/fgene.2013.00247.
  • Human-specific endogenous retroviral insert serves as an enhancer for the schizophrenia-linked gene PRODH. Suntsova M, Gogvadze EV, Salozhin S, Gaifullin N, Eroshkin F, Dmitriev SE, Martynova N, Kulikov K, Malakhova G, Tukhbatova G, Bolshakov AP, Ghilarov D, Garazha A, Aliper A, Cantor CR, Solokhin Y, Roumiantsev S, Balaban P, Zhavoronkov A, Buzdin A. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19472-7. IF: 9.8
  • Experimental analysis of human specific protein coding open reading frame c11orf72. Baskaev KK, Kholodenko RV, Malakhova GV, Gaĭfullin NM, Korzeneva EA, Suntsova MV, Buzdin AA. Bioorg Khim. 2013 Mar-Apr;39(2):151-8. Russian. IF: 0.6
  • LINE-1 retrotransposable element DNA accumulates in HIV-1-infected cells. Jones RB, Song H, Xu Y, Garrison KE, Buzdin AA, Anwar N, Hunter DV, Mujib S, Mihajlovic V, Martin E, Lee E, Kuciak M, Raposo RA, Bozorgzad A, Meiklejohn DA, Ndhlovu LC, Nixon DF, Ostrowski MA. Journal of Virology 2013 Dec;87(24):13307-20. doi: 10.1128/JVI.02257-13. Epub 2013 Oct 2.  IF: 4.6
  • Characteristic patterns of microRNA expression in human bladder cancer. Zabolotneva AA, Zhavoronkov A, Garazha AV, Roumiantsev SA, Buzdin AA. Front Genet. 2013 Jan 4;3:310. doi: 10.3389/fgene.2012.00310. eCollection 2012.
  • Sense transcripts originated from an internal part of the human retrotransposon LINE-1 5' UTR. Alexandrova EA, Olovnikov IA, Malakhova GV, Zabolotneva AA, Suntsova MV, Dmitriev SE, BuzdinAA. Gene. 2012 Dec 10;511(1):46-53. IF: 2.1
  • Transcriptional regulation of human-specific SVA(F1) retrotransposons by cis-regulatory MAST2 sequences. Zabolotneva AA, Bantysh O, Suntsova MV, Efimova N, Malakhova GV, Schumann GG, Gayfullin NM,Buzdin AA. Gene. 2012 Aug 15;505(1):128-36. Epub 2012 May 15. IF: 2.1
  • nMETR: Technique for facile recovery of hypomethylation genomic tags. Baskaev K, Garazha A, Gaifullin N, Suntsova MV, Zabolotneva AA, Buzdin AA. Gene. 2012 Apr 25;498(1):75-80. Epub 2012 Feb 13. IF: 2.1
  • How many antiviral small interfering RNAs may be encoded by the mammalian genomes? A. Zabolotneva, V. Tkachev, F. Filatov, A. Buzdin (2010)Biology Direct 5: 62 doi:10.1186/1745-6150-5-62 IF: 4.03
  • Unique functions of the repetitive transcriptome. G.G. Schumann, E.V. Gogvadze, M. Osanai-Futahashi, A. Kuroki, C. Münk, H. Fujiwara, Z. Ivics, and A.A. Buzdin. (2010) International Review of Cell and Molecular Biology, Vol. 285:115-88. IF: 4.97
  • Novel strong tissue specific promoter for gene expression in human germ cells. Kuzmin D, Gogvadze E, Kholodenko R, Grzela DP, Mityaev M,Vinogradova T, Kopantzev E, Malakhova G, Suntsova M, Sokov D, Ivics Z, Buzdin A. (2010) BMC Biotechnol. 2010 Aug 17;10(1):58. IF: 2.6
  • Enhancer element potentially involved in human survivin gene promoter regulation in lung cancer cell lines. Mityaev MV, Kopantzev EP, Buzdin AA, Vinogradova TV, Sverdlov ED. (2010) Biochemistry (Mosc). 2010 Feb;75(2):182-91. IF: 1.4
  • Functional analysis of endogenous retroviral inserts in the context of human genome evolution. A.A. Buzdin (2010), Russian Journal of Bioorganic Chemistry, 36(1): 35-43. IF: 0.6
  • HIV-1 infection induces retrotransposition of LINE-1 elements. Jones RB, Garrison KE, Song H, Buzdin A, Anwar N, Meiklejohn DA, Ndhlovu LC,Nixon DF, Ostrowski MA (2009) Retrovirology, 6(S2): P32. IF: 4.8
  • Novel family of human transposable elements formed due to a fusion of the first exon of gene MAST2 with retrotransposon SVA. O.B. Bantysh, A.A. Buzdin (2009) Biochemistry (Mosc).74(12):1709-1717. IF: 1.4
  • Retroelements and their impact on genome evolution and functioning. Gogvadze E., Buzdin A. (2009) CMLS, Cell. Mol. Life Sci. Aug.2. IF: 5.9
  • Human-specific modulation of transcriptional activity provided by endogenous retroviral inserts. E Gogvadze, E Stukacheva, A Buzdin, and E Sverdlov (2009) J.Virol. 83(12): 6098-6105. IF: 4.6
  • Molecular receptors of taste agents. D.A. Ghilarov, T.A. Sakharova, A.A. Buzdin. (2009) Russian Journal of Bioorganic Chemistry, 35(1): 5-14. IF: 0.6
  • Functional significance of a putative sp1 transcription factor binding site in the survivin gene promoter. Mityaev MV, Kopantzev EP, Buzdin AA, Vinogradova TV, Sverdlov ED. Biochemistry (Mosc). 2008 Nov;73(11):1183-91. IF: 1.3
  • E. Gogvadze, C.  Barbisan, M.-H.  Lebrun and A. Buzdin (2007) Tripartite chimeric pseudogene from the genome of rice blast fungus Magnaporthe grisea suggests double template jumps during long interspersed nuclear element (LINE) reverse transcription. BMC Genomics, 8(1):360. IF: 4.04
  • A. Buzdin (2007) Human specific endogenous retroviruses. TheScientificWorldJournal, 7: 1848-1868.
  • Buzdin A, Gogvadze E, Lebrun MH. (2007) Chimeric retrogenes suggest a role for the nucleolus in LINE amplification. FEBS Lett., 581(16):2877-82. Epub 2007 May 25. IF: 3.5
  • I. Kholodenko, R. Kholodenko, V. Sorokin, A. Tolmazova, O. Sazonova, A. Buzdin (2007) Anti-apoptotic effect of retinoic acid on retinal progenitor cells mediated by a protein kinase A-dependent mechanism. Cell Research,  17(2):151-62. IF: 11.98
  • Buzdin A., Kovalskaya-Alexandrova E., Gogvadze E., Sverdlov E. (2006) At Least 50% of Human-Specific HERV-K (HML-2) Long Terminal Repeats Serve In Vivo as Active Promoters for Host nonrepetitive DNA Transcription. J Virol., 80(21):10752-62. IF: 4.6
  • A. Buzdin, E. Kovalskaya-Alexandrova, E. Gogvadze, E. Sverdlov (2006) GREM, a technique for genome-wide isolation and quantitative analysis of promoter active repeats. Nucleic Acids Res., 34(9): e67. IF: 8.8
  • I. V. Kholodenko, A. A. Buzdin, R. V. Kholodenko, J. A. Bibikova, V. F. Sorokin, V. N. Yarygin, and E. D. Sverdlov (2006) Mouse retinal progenitor cell (RPC) cocultivation with retinal pigment epithelial cell culture affects features of RPC differentiation. Biochemistry (Moscow) 71(7):767-74. IF: 1.3
  • Kovalskaya, E., Buzdin, A., Gogvadze, E., Vinogradova, T., Sverdlov, E.D. (2006) Functional human endogenous retroviral LTR transcription start sites are located between the R and U5 regions. Virology,  Mar 15; 346(2):373-378. IF: 3.3
  • Buzdin, A. (2006) Transposable elements and their use for target site specific gene delivery. Current Pharmacogenomics, March; 4(1): 1-8.
  • Gogvadze, E., Buzdin, A. (2005) New mechanism of retrogene formation in mammalian genomes: in vivo recombination during RNA reverse transcription. Molecular Biology (Moscow), May-Jun;39(3):364-373. IF: 0.7
  • Buzdin, A., Vinogradova, T., Lebedev, Y., Sverdlov, E. (2005) Genome-wide experimental identification and functional analysis of human specific retroelements. Cytogenet. Genome Res.;110(1-4):468-474., in the special issue: "Retrotransposable elements and genome evolution". IF: 1.9
  • Gogvadze, E., Buzdin, A., Sverdlov, E. (2005) Multiple template switches during LINE directed reverse transcription is a general mechanism of the chimeric retroelement formation in mammals. Russian Journal of Bioorganic Chemistry, 31(1):82-89. IF: 0.6
  • Chalaya T., Gogvadze E., Buzdin A., Kovalskaya E., Sverdlov E.D. (2004). Improving specificity of DNA hybridization-based methods. Nucleic Acids Res., 32(16):e130. IF: 8.8
  • Buzdin, A. (2004) Retroelements and formation of chimeric retrogenes. CMLS, Cell. Mol. Life Sci. 61(16):2046-2059. IF: 5.9
  • Buzdin, A., Gogvadze, E., Kovalskaya, E., Volchkov, P., Ustyugova, S., Illarionova, A., Fushan, A., Vinogradova, T., Sverdlov, E. (2003) The human genome contains many types of chimeric retrogenes generated through in vivo RNA recombination. Nucleic Acids Res., 31(15):4385-4390. IF: 8.8
  • Buzdin, A., Lebedev, Yu., Sverdlov, E. (2003) Human specific HERV-K LTRs in gene introns have a non-random orientation and, possibly, participate in antisense regulation of the gene expression. Russian Journal of Bioorganic Chemistry, 29(1):103-106. IF: 0.6
  • Buzdin, A., Ustyugova, S., Khodosevich, K., Mamedov, I., Lebedev, Y., Hunsmann, G., Sverdlov, E. (2003) Human-specific subfamilies of HERV-K (HML-2) long terminal repeats: three master genes were active simultaneously during branching of hominoid lineages. Genomics, 81(2):149-156. IF: 2.8
  • Buzdin, A., Ustyugova, S., Gogvadze, E., Lebedev, Y., Hunsmann, G., Sverdlov, E. (2003) Genome-wide targeted search for human specific and polymorphic L1 integrations. Human Genetics, 112(5-6):527-533. IF: 4.5
  • Buzdin, A., Ustyugova, S., Gogvadze, E., Vinogradova, T., Lebedev, Y., Sverdlov, E. (2002) A new family of chimeric retrotranscripts formed by a full copy of U6 small nuclear RNA fused to the 3' terminus of L1. Genomics, 80(4):402-406. IF: 2.8
  • Mamedov, I., Batrak, A., Buzdin, A., Arzumanyan, E., Lebedev, Y., Sverdlov, E. (2002) Genome-wide comparison of differences in the integration sites of interspersed repeats between closely related genomes. Nucleic Acids Res., 30(14):e71. IF: 8.8
  • Buzdin, A., Revina, L., Kostina, L., Zalunin, I., Chestukhina, G. (2002) Interaction of 65- and 62-kD proteins from the apical membranes of the Aedes aegypti larvae midgut epithelium with Cry4B and Cry11A endotoxins of Bacillus thuringiensis. Biochemistry (Moscow), 67(5):540-546. IF: 1.3
  • Buzdin, A., Khodosevich, K., Mamedov, I., Vinogradova, T., Lebedev, Y., Hunsmann, G., Sverdlov, E. (2002) A technique for genome-wide identification of differences in the interspersed repeats integrations between closely related genomes and its application to detection of human-specific integrations of HERV-K LTRs. Genomics, 79(3):413-422. IF: 2.8
  • Krieger, I., Revina, L., Kostina, L., Buzdin, A., Zalunin, I., Chestukhina, G., Stepanov, V. (1999) Membrane proteins of Aedes aegypti larvae bind toxins Cry4B and Cry11A of Bacillus thuringiensis ssp. israelensis. Biochemistry (Moscow), 64(10):1163-1168. IF: 1.3
  1. Recent Inserts of Transposable Elements Affect Structure and Functions of Human Genome. Anton Buzdin, Maria Suntsova, Olga Bantysh, Elena Aleksandrova, Anastasia Zabolotneva, Elena Gogvadze, and Nurshat Gaifullin (2012) Chapter 23 in Book “Radiobiology and environmental security”, eds. C.E. Mothersill, V. Korogodina and C.B. Seymour. Springer, ISBN 978-94-007-1999-6 (PB) p: 269-297.
  2. D.A. Ghilarov, A.А. Buzdin. Endogenous retroviral sequences control the transcription of many host genes in eukaryotes (2009). Chapter in the book “Viral Genomes: Diversity, Properties and Parameters” Nova Science Publishers (USA) Pages: 35-63. ISBN: 978-1-60741-067-6
  3. Monograph “Nucleic acids hybridization: modern applications”. Editors: Anton Buzdin, Sergey Lukyanov; Springer (2007) ISBN 978-1-4020-6039-7.
  4. Nucleic acids hybridization: potentials and limitations (Anton Buzdin) Chapter in the book “Nucleic acids hybridization: modern applications”. Editors: Anton Buzdin, Sergey Lukyanov, Springer (2007) ISBN 978-1-4020-6039-7.
  5. Selective suppression of polymerase chain reaction and its most popular applications (Sergey Lukyanov, Konstantin Lukyanov, Nadezhda Gurskaya, Ekaterina Bogdanova, Anton Buzdin). Chapter in the book “Nucleic acids hybridization: modern applications”. Editors: Anton Buzdin, Sergey Lukyanov, Springer (2007) ISBN 978-1-4020-6039-7.
  6. Suppression subtractive hybridization (Sergey Lukyanov, Denis Rebrikov,  Anton Buzdin). Chapter in the book “Nucleic acids hybridization: modern applications”. Editors: Anton Buzdin, Sergey Lukyanov, Springer (2007) ISBN 978-1-4020-6039-7.
  7. Stem-loop oligonucleotides as hybridization probes and their practical use in molecular biology and biomedicine (Anton Buzdin, Sergey Lukyanov). Chapter in the book “Nucleic acids hybridization: modern applications”. Editors: Anton Buzdin, Sergey Lukyanov, Springer (2007) ISBN 978-1-4020-6039-7.
  8. Coincidence cloning: robust technique for isolation of common sequences (Anton Buzdin). Chapter in the book “Nucleic acids hybridization: modern applications”. Editors: Anton Buzdin, Sergey Lukyanov, Springer (2007) ISBN 978-1-4020-6039-7.
  9. DNA hybridization in solution for mutation detection (Anton Buzdin) Chapter in the book “Nucleic acids hybridization: modern applications”. Editors: Anton Buzdin, Sergey Lukyanov, Springer (2007) ISBN 978-1-4020-6039-7.
  10. Current attempts to improve the specificity of nucleic acids hybridization (Anton Buzdin). Chapter in the book “Nucleic acids hybridization: modern applications”. Editors: Anton Buzdin, Sergey Lukyanov, Springer (2007) ISBN 978-1-4020-6039-7.